Most Cancer Treatments Are Not Effective Victims of Mesothelioma, However Photodynamic Therapy May Be a Promising Alternative
Oncologists and other cancer doctors decide what kind of treatment to prescribe to their patient. The options are endless. There are no one size fits all treatment regimen for peritoneal mesothelioma patients. This is because of the relative rareness of the disease, the high mortality rate and low treatment success rate, and the few scientific studies to provide meaningful statistics.
While prospects for patients with mesothelioma have been bleak, doctors have been making progress. Traditional treatments for cancer are surgery (removing the tumor and surrounding tissue), chemotherapy (poisoning cancerous cells) and radiation (killing cancer cells with radiation) There are problems with all three. Patients with mesothelioma have not responded well to traditional radiation therapy. Researchers are looking for ways of aiming radiation directly at the tumor in hopes that this will result in less damage to healthy tissue.
Surgery takes out the mesothelial cancerous tissue around the tumor. The surgery is difficult and challenging, with unknown effects or benefits to patients. Common chemotherapy drugs that work on other types of cancer usually do not work on mesothelioma, and different combinations of chemotherapy drugs have been tried without a lot of success. Similar to radiation, focus in research is focusing on treating the physical location of the tumor with emphasis on the pleural cavity.
The high-mortality rate for mesothelioma patients means cutting-edge techniques for cancer are tried out. These include biologic therapy such as the agent interleukin 2 and anti-angiogenesis drugs such as thalidomide. Pemetrexed (Alimta) is a new drug that has shown results in extending life.
Oncologists consider the stage of mesothelioma, the location of the tumor, the patient’s age and state of health at the time. Two therapies that are extremely cutting-edge in fighting cancer are called photodynamic and gene therapy. Patients afflicted with mesothelioma are benefitting in these clinical trials.
